Cayman Chemical S-Ibuprofen 1g
A muscarinic M3 receptor antagonist (Ki 0.76 nM) selective for M3 over M1 M2 M4 and M5 mAChRs (Kis 7.08 44.67 45.71 and 9.33 nM respectively) selectively inhibits contractions in isolated guinea pig ileum bladder and trachea (pA2s 9.44 8.66 and 8.7 respectively) over isolated rabbit vas deferens and isolated guinea pig atria (pA2s 7.9 and 7.48 respectively) inhibits micturition pressure (ED50 0.089 mg/kg i.v.) as well as micturition interval and volume in rats